leader Tóth István Balázs
The main research focus of our group is the investigation of thermo- and mechanosensitive ion channels expressed in peripheral tissues and somatosensory neurons, as well as their associated signaling pathways in various inflammatory processes. We aim to achieve a better understanding of the molecular mechanisms of inflammation and to identify novel pharmacological targets.
Most of our experiments are performed on primary isolated human cells, mouse sensory neurons, and cell lines expressing recombinant ion channels. Among other methods, we mainly apply intracellular calcium imaging, patch-clamp electrophysiology, and a variety of molecular biological techniques.
Our current research projects focus on inflammatory processes developing in the oral cavity and dental pulp, as well as in human skin. We also study the pharmacology of selected sensory TRP ion channels.
Dr. Henn-Mike Nóra (research associate)
Jasper Viktor (biologist)
Gauzer Szandra (undergraduate student)
Ráth Péter (undergraduate student)
Kovács Natasa (undergraduate student)
Hrabovszki Kitti (Financial Administrator)