The group conducts multidisciplinary research with high translational value. Our experimental subjects are laboratory mice and rats, but we also collaborate with groups conducting human studies. In addition to detailed behavioral phenotyping, we follow the hormonal consequences of stressors using endocrinological methods. We study stress-induced autonomic nervous system changes using in vivo biotelemetry. We use immunohistochemistry, PCR, as well as opto- and pharmacogenetic methods and epigenetic approaches to uncover brain mechanisms. We investigate the possibilities of drug treatment based on the revealed neuronal connections and mechanisms using behavioral pharmacological methods. Along these lines, we work on three main research topics: 1. post-traumatic stress disorder as a metabolic disease; 2. The role of the median raphe nucleus and its specific cells in behavior using Cre mice, opto- and pharmacogenetic techniques; 3. Characterization of the 3xTg-AD mouse model of Alzheimer's disease, identification of new drug targets.
leader: Prof. Dr. Zelena Dóra
Dr. Farkas Szidónia
Péliné Dr. Kovács Anita
Dr. Hencz Alexandra
Dr. Plangár Imola
Szabó Adrienn
Várkonyi Dorottya
Dr. Szabó Evelin
Prabhat Kumar
Kvak Erika
Makkai Bernadett
Varga Réka