(leader: Dr. Kecskés Miklós)
The main area of interest of the research group is the study of the brain expression and function of Transient Receptor Potential (TRP) ion channels. The TRP ion channel family includes 28 members in mammals. The understanding of TRP ion channels was made possible by the study of TRPV1, TRPA1 and TRPM8 channels located on peripheral nerve terminals. These classical receptors play a role in, among others, the perception of cold and heat, the transmission of inflammatory pain, but also in the perception of the pungency of chili peppers.
However, the brain expression and function of TRP ion channels is still a poorly explored area, especially with regard to the expression pattern at the cellular level. The focus of our research is on neurons expressing TRP ion channels from different brain areas, including the hippocampus, the amygdala and the piriform cortex.
We use modern neuroscience techniques to study ion channels, such as in vitro and in vivo electrophysiology, Ca2+ imaging and immunohistochemistry.
Mundrucz Laura
Gyéresi Attila
Deák Máté
Hrabovszki Kitti (intézeti gazdasági ügyintéző, 1/4)